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  • Pure Encapsulations® Nrf2 Detox, 60 vcaps

Pure Encapsulations® Nrf2 Detox, 60 vcaps

SKU: NRF6
$54.80
$54.80
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Pure Encapsulations® Nrf2 Detox is a three-ingredient detox formula designed to help stimulate detoxification and support antioxidant defenses. Nrf2 Detox specifically supports detoxification processes in the liver and promotes proper enzyme function, transport, and cell maturation. Order your bottle today!
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Quality & Purity
Pure Encapsulations® manufactures a line of hypoallergenic, research-based dietary supplements that are designed to deliver predictable and desired results to help your body operate at its fullest potential. Pure Encapsulations® is committed to sourcing pure, premium ingredients to help you achieve optimal health. Products are nothing but pure. Dietary supplements are formulated with premium raw ingredients and are scientifically tested to ensure that each ingredient and final product meets quality standards. All Pure Encapsulations® products are free from wheat and gluten; eggs; peanuts; coatings and shellacs; GMOs; magnesium stearate; trans fats and hydrogenated oils; artificial colors, flavors, and sweeteners; and unnecessary binders, fillers, and preservatives. Pure Encapsulations® source premium raw materials from trusted industry leaders, including the finest suppliers from the United States, France, Japan, Switzerland, Germany, and Italy. All ingredients are tested for purity and potency by independent certified laboratories. Ingredient suppliers must meet rigorous testing and quality criteria to quality as a Pure Encapsulations® supplier. 

This product is manufactured according to the cGMP Standards and Inspection. Tests before, during, and after processing guarantee uniform quality and purity. Quality manufacturing practices are essential to the integrity of professionally oriented natural health products. That is why our dispensary is independently registered by NSF® to meet cGMP requirements for the brands we carry. NSF International audits each of our facilities twice per year. Together, we offer industry-leading shipping times and reliability. Orders placed before 4:30 PM EST are processed and shipped the same day and will arrive at your door within days.

What is Nrf2 Detox?
  • Nrf2 Detox contains a combination of glutathione, sulforaphane from broccoli sprout concentrate, and resveratrol to promotedetoxification and antioxidant defenses. This formula is designed to target Nrf2 (nuclear factor erythroid 2-related factor 2), a transcription factor that acts as a genomic “switch” and master inducer of more than 1,000 genes throughout the body, helping to protect against toxins, reactive metabolites, reactive oxygen species and environmental xenobiotics.

Special Features for Nrf2 Detox
  • Offers Setria glutathione, the only brand of glutathione with research showing absorption
  • Contains 1,000 mcg sulforaphane from broccoli, one of the most powerful activators of phase II enzyme function; also supports antoxidant activity (i.e. SOD)
  • Includes resveratrol to support cellular function and healthy genomic expression
  • Vegetarian

Uses for Nrf2 Detox
  • Detoxification: Cruciferous vegetables of the brassica family have long been recognized for their ability to support detoxification thereby maintaining healthy cells and tissues. Cruciferous vegetables, like broccoli, cauliflower, Brussels sprouts and kale, are the richest sources of glucosinolates, which are considered to be the most bioactive constituents. Glucosinolates are converted in the body to isothiocyanates after they are ingested and hydrolyzed. The isothiocyanate sulforaphane is one of the most powerful activators of phase II enzyme function in the liver, supporting toxin elimination. Sulforaphane and resveratrol promote the activity of nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that supports robust, long-lasting expression of numerous genes responsible for detoxification and protection against oxidative stress. Among these genes are glutathione peroxidase, superoxide dismutase and various phase II enzymes, such as glutathione sulfotransferases. Nrf2 also supports expression of glutathione glutamylcysteinyl ligase, which is responsible for a critical step in the biosynthesis of glutathione, a vital component of phase II detoxification. The highest concentration of glutathione is found in the liver, where it offers antioxidant support, protects tissue and maintains detoxification.
  • Cellular Health: Glutathione is also a vital component of cellular antioxidant systems. Found in virtually every cell of the body, glutathione plays essential roles in protein synthesis, synthesis and repair of DNA, enzyme function, transport, and cell maturation. Optimal levels of glutathione have been associated with physical and mental health. In a randomized clinical trial, supplementation with 250 and 1,000 mg of Setria® glutathione per day increased glutathione levels in the blood after one, three and six months. At six
    months, mean glutathione levels in the high-dose group increased 30–35% in erythrocytes, plasma and lymphocytes, and 260% in buccal cells (P<0.05). In the low-dose group, mean glutathione levels increased 17% and 29% in blood and erythrocytes, respectively (P<0.05). Both glutathione dose groups showed support for antioxidant defenses, indicated by decreases in the oxidized-toreduced-glutathione ratio in whole blood after six months.

Potential Side Effects or Precautions
  • If pregnant or lactating, consult your physician before taking this product.
  • It is recommended to use resveratrol cautiously in patients with hormonal disorders and those using estrogen therapy, as resveratrol may act as either an estrogen agonist or estrogen antagonist.
  • Consult your physician for more information.

Potential Drug Interactions
  • Some studies have reported that broccoli sprout extract can affect the way that the liver breaks down medications metabolized by the cytochrome P450 system, altering the effects of these medications and possibly the dose needed for treatment.
  • Resveratrol and broccoli sprout extract may react with blood thinning medications.
  • Consult your physician for more information.
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